Drugs & Vitamins

WR-2721 Active Ingredients: Amifostine Injection   Representative Names: Ethiofos, Ethyol, WR-2721 What is amifostine? What should I tell my health care provider before I take this medicine? How should I receive this medicine? What if I miss a dose? What drug(s) may interact with amifostine? What side effects may I notice from receiving amifostine? What should I watch for while taking amifostine? Where can I keep my medicine? What is amifostine? (Back to top) AMIFOSTINE (Ethyol®) is used to decrease the side effects of chemotherapy or radiation therapy. Generic amifostine is not yet available. What should I tell my health care provider before I take this medicine? (Back to top) They need to know if you have any of these conditions: •heart disease, including heart failure •history of stroke or TIAs •irregular heart beats •low blood pressure •low calcium •taking medicine for high blood pressure •an unusual or allergic reaction to amifostine, other medicines, foods, dyes, or preservatives •pregnant or trying to get pregnant •breast-feeding How should I receive this medicine? (Back to top) Amifostine is given as an infusion into a vein by a health care professional in a hospital or clinic setting. Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed. What if I miss a dose? (Back to top) This does not apply. What drug(s) may interact with amifostine? (Back to top) •medicines to lower blood pressure Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines. What side effects may I notice from receiving amifostine? (Back to top) Side effects that you should report to your prescriber or health care professional as soon as possible: •chest pain or tightness •difficulty breathing •dizziness, lightheadedness or feeling faint (signs of low blood pressure during treatment) •irregular heart beats or palpitations •nausea/vomiting •rash or hives •redness, blistering, peeling or loosening of the skin, including inside the mouth •seizures Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome): •flushing •hiccups •sneezing What should I watch for while taking amifostine? (Back to top) Your condition will be closely monitored while you receive amifostine. Visit your prescriber or health care professional for regular checks on your progress. Where can I keep my medicine? (Back to top) Amifostine will be given in a hospital or clinic setting prior to chemotherapy or radiation therapy. You will not take this medicine at home. Last Updated:07/22/2002 CLINICAL PHARMACOLOGY© GOLD STANDARD MULTIMEDIA INC, ALL RIGHTS RESERVED

Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It should not be construed to indicate that the use of the product is safe, appropriate, or effective for you. Consult your healthcare professional before taking the product.